Over the last decade the UK government has been promoting the concept of Evidence-based policy (EBP). Our partners in the South constantly ask about what is happening in the UK regarding EBP and what can they learn from the UK experience. The aim of this work is to identify lessons and approaches from EBP in the UK which may be valuable to developing countries. The issues, approaches and tools presented are based on the assumption that the reader is a progressive policymaker in a developing country, who is interested in utilising EBP. The focus is on policymakers within the public sector, rather than those working within the private sector or civil society.