This strategy presents challenges and unprecedented opportunities for data, evaluation, and research to inform policy in low- and middle-income countries. We describe the common ingredients needed for governments to increase the use of evidence in their policy decisions. We outline an approach to grantmaking and other activities “beyond the grant dollars” to build the field of evidence-informed policymaking. We also identify how we will track progress and highlight some of the risks that may affect our grantees’ work and how successful this approach is.